Curam 312.5 Mg / 5 Ml Susp 75 Ml

Curam 312.5 Mg 75 ml

Description:

Curam 312.5 mg/5 ml powder for oral suspension 75 ml is a prescription systemic antibiotic medicine containing amoxicillin and clavulanic acid. It belongs to the beta-lactam/penicillin class and is used to treat a wide range of bacterial infections, particularly those caused by beta-lactamase–producing organisms that are resistant to amoxicillin alone. After reconstitution, it is taken by mouth as a flavored oral suspension, commonly prescribed for children and adults who have difficulty swallowing tablets. Curam is indicated for infections of the respiratory tract, ear, sinuses, skin, and urinary tract, when caused by susceptible bacteria.

Indications:

• Lower respiratory tract infections (such as bronchitis and pneumonia) caused by beta-lactamase–producing isolates of Haemophilus influenzae and Moraxella catarrhalis.
• Acute bacterial otitis media (middle ear infection) caused by beta-lactamase–producing isolates of H. influenzae and M. catarrhalis.
• Acute bacterial sinusitis caused by beta-lactamase–producing isolates of H. influenzae and M. catarrhalis.
• Skin and skin structure infections caused by beta-lactamase–producing isolates of Staphylococcus aureus, Escherichia coli, and Klebsiella species.
• Urinary tract infections (UTIs) caused by beta-lactamase–producing isolates of E. coli, Klebsiella species, and Enterobacter species.
• Other infections as determined appropriate by the prescribing physician based on culture, sensitivity, and local antibiotic guidelines.

Active Ingredients / Key Components:

• Amoxicillin – 250 mg per 5 ml (after reconstitution) (information based on standard Curam 312.5 mg/5 ml formulation; if local pack differs, follow local label). Exact concentration per 5 ml may vary by market; please refer to the package insert for confirmed strength.
• Clavulanic acid (as potassium clavulanate) – 62.5 mg per 5 ml (after reconstitution) (information based on standard Curam 312.5 mg/5 ml formulation; if local pack differs, follow local label).
• Total stated strength: 312.5 mg/5 ml (amoxicillin + clavulanic acid combined).
• Inactive ingredients (excipients): full list not available in the provided data. Typically includes sweeteners, flavoring agents, suspending agents, and stabilizers. Please check the product leaflet for the complete excipient list.

Dosage & Administration / How to Use:

• This product is for oral use only, after reconstitution to an oral suspension by a pharmacist or as directed on the pack.
• Shake the bottle well before each use to ensure uniform suspension.
• Dosage is usually based on the amoxicillin component, the type and severity of infection, and the patient’s body weight and age. Follow your doctor’s exact instructions.
• Typical pediatric dosing (example only – not a substitute for prescription): often calculated as mg/kg/day divided into 2–3 doses. The prescriber will determine the exact dose and frequency.
• Adults and adolescents: dose and frequency are determined by the physician according to infection type and severity and local guidelines.
• Curam oral suspension is generally taken at the start of a meal to improve absorption and reduce potential gastrointestinal side effects.
• Use the provided measuring spoon or oral syringe for accurate dosing. Do not use household teaspoons.
• Duration of treatment is usually 5–14 days depending on the infection and clinical response. Do not stop treatment early even if symptoms improve, unless advised by your doctor.
• If a dose is missed, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and continue with the regular schedule. Do not double the dose.
• Do not use this medicine without a doctor’s prescription and do not share it with others.

Clinical Benefits:

• Broad-spectrum antibacterial coverage against many common respiratory, ear, sinus, skin, and urinary pathogens.
• Effective against beta-lactamase–producing bacteria due to the clavulanic acid component, which protects amoxicillin from enzymatic breakdown.
• Helps rapidly reduce infection-related symptoms such as fever, pain, cough, sore throat, earache, sinus pressure, and urinary discomfort when caused by susceptible bacteria.
• Oral suspension form is suitable for children and adults who have difficulty swallowing tablets, improving treatment adherence.

Warnings & Contraindications:

• Contraindicated in patients with a known allergy (hypersensitivity) to amoxicillin, clavulanic acid, other penicillins, or any component of the formulation.
• Use with extreme caution in patients with a history of severe allergic reactions to beta-lactam antibiotics (e.g., cephalosporins, carbapenems). Serious reactions, including anaphylaxis, can occur.
• Contraindicated in patients with a history of jaundice or liver dysfunction associated with amoxicillin/clavulanic acid use.
• Use with caution in patients with liver impairment or kidney impairment; dose adjustment may be required. Physician supervision is essential.
• Antibiotic-associated colitis (including Clostridioides difficile–associated diarrhea) may occur. If severe, persistent diarrhea or abdominal cramps develop, stop the medicine and contact a doctor immediately.
• Prolonged or repeated use may result in overgrowth of non-susceptible organisms, including fungi. Medical monitoring is recommended for long courses.
• Consult your doctor before use if pregnant or planning pregnancy. Use during pregnancy should be based on a risk–benefit assessment by the physician.
• Consult your doctor before use if breastfeeding; small amounts of amoxicillin and clavulanic acid may pass into breast milk and may affect the infant (e.g., diarrhea, candidiasis).
• Inform your doctor about all other medicines you are taking, especially anticoagulants (e.g., warfarin), allopurinol, methotrexate, or other antibiotics, due to potential interactions.
• May interfere with some laboratory tests (e.g., urine glucose tests using non-enzymatic methods). Inform laboratory staff that you are taking this medicine.
• Not intended to diagnose, treat, cure, or prevent any disease without proper medical supervision and prescription.
• Keep out of reach of children.

Side Effects:

• Common side effects: nausea, vomiting, diarrhea, abdominal discomfort, soft stools, and mild skin rash.
• Less common side effects: headache, dizziness, oral or vaginal candidiasis (thrush), changes in taste.
• Allergic reactions: rash, itching, hives, swelling of the face, lips, tongue, or throat, difficulty breathing or swallowing. These may indicate a serious allergic reaction; seek emergency medical attention immediately.
• Serious but rare side effects: severe skin reactions (e.g., Stevens–Johnson syndrome), severe persistent diarrhea (possible antibiotic-associated colitis), liver problems (jaundice, dark urine, severe fatigue, abdominal pain), blood disorders (unusual bruising or bleeding). Stop the medicine and contact a doctor immediately if these occur.
• If any side effects are severe, persistent, or concerning, contact your healthcare provider promptly.

Storage Instructions:

Store the unopened powder in a cool, dry place away from direct sunlight and moisture. Keep the bottle tightly closed. After reconstitution, store the prepared suspension in a refrigerator (2–8 °c) if recommended by the local product leaflet, and use within the period specified on the label (commonly 7–10 days). Do not freeze. Discard any unused suspension after the recommended in-use period. Keep out of reach of children.

Specifications:

• Product type: systemic antibiotic medicine (oral suspension after reconstitution).
• Strength: 312.5 mg/5 ml (amoxicillin + clavulanic acid combined) – exact split per 5 ml as per local label.
• Volume: 75 ml (final volume of suspension after reconstitution, as indicated on pack).
• Route of administration: oral.
• Suitable for: adults and children as prescribed by a healthcare professional.

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.