Insulin Mixtard Penfill 30 100 I.U 5 Vials

Insulin Mixtard Penfill 30 100 I.U 5 Vials

Description:

Insulin Mixtard Penfill 30 100 i.u 5 vials is a prescription human insulin medicine used for the management of diabetes mellitus. It is a biphasic insulin preparation containing a mixture of short-acting soluble human insulin and intermediate-acting isophane (NPH) human insulin, designed for use in compatible insulin pens. This combination provides both rapid onset and prolonged duration of blood glucose control, helping to regulate fasting and post-meal (postprandial) blood sugar levels in adults and children with type 1 and type 2 diabetes. It is used as an adjunct to diet, exercise, and regular blood glucose monitoring under medical supervision.

Indications:

• Indicated as an adjunct to diet and exercise to improve glycemic control in adults and children with type 1 diabetes mellitus.
• Indicated as an adjunct to diet and exercise to improve glycemic control in adults and children with type 2 diabetes mellitus when oral antidiabetic agents alone are insufficient.
• Helps control fasting and postprandial hyperglycemia (high blood sugar).
• Prevention of acute complications of uncontrolled diabetes such as diabetic ketoacidosis and hyperosmolar states when used as part of a comprehensive diabetes management plan.

Active Ingredients / Key Components:

• Human insulin (biphasic mixture) – 100 iu/ml (total) in each vial.
• Insulin neutral human (soluble human insulin) – 30% of total insulin content (30 iu/ml).
• Insulin isophane protamine human (NPH human insulin) – 70% of total insulin content (70 iu/ml).
• Excipients (such as protamine, zinc, glycerol, metacresol, phenol, and others) are typically present to stabilize the insulin solution/suspension; exact excipient list and concentrations , please check the product leaflet or the manufacturer’s official website and should be checked on the official package leaflet.

Dosage & Administration / How to Use:

• Dosage must always be individualized by a physician based on blood glucose monitoring, type of diabetes, body weight, diet, physical activity, and concomitant medications.
• Insulin Mixtard Penfill 30 is administered by subcutaneous injection only; do not inject intravenously or intramuscularly unless specifically instructed by a healthcare professional.
• Common injection sites: abdomen, thigh, upper arm, or buttock. Rotate injection sites within the same region to reduce risk of lipodystrophy (fat tissue changes).
• Typically injected once or twice daily, usually shortly before a meal. Exact timing (e.g., within 30 minutes before eating) must follow your doctor’s instructions.
• Use only with compatible insulin pen devices designed for Penfill cartridges/vials; follow the pen manufacturer’s instructions for loading, priming, and dose setting.
• Check the insulin before use: the suspension should appear uniformly cloudy and white after gentle rolling between the hands. Do not use if clumps, particles, or clear liquid remain separated after mixing, or if the vial is damaged.
• Do not share insulin pens, cartridges, or needles with anyone, even if the needle is changed, to avoid cross-infection.
• Never change your insulin dose, insulin type, or injection schedule without consulting your doctor or diabetes nurse.
• In case of missed dose, monitor blood glucose closely and follow your healthcare provider’s advice; do not double the next dose without medical guidance.

Clinical Benefits:

• Provides both rapid and intermediate insulin action in a single preparation, simplifying insulin regimens for many patients.
• Helps achieve more stable glycemic control, reducing episodes of hyperglycemia when used correctly with diet and exercise.
• Supports long-term reduction in the risk of diabetes-related complications such as neuropathy, nephropathy, and retinopathy when part of tight glycemic control.
• Convenient Penfill format allows accurate dose adjustment and easier administration compared with traditional vials and syringes.

Warnings & Contraindications:

• Contraindicated in patients with known hypersensitivity to human insulin or any of the excipients in the formulation.
• Do not use during episodes of hypoglycemia (low blood sugar). Blood glucose must be corrected before insulin administration.
• Use with extreme caution in patients with impaired kidney or liver function, adrenal, pituitary, or thyroid disorders; dose adjustments may be required.
• Concomitant use of other antidiabetic medicines (oral agents, GLP-1 agonists, SGLT2 inhibitors, etc.) or drugs affecting blood glucose (e.g., corticosteroids, beta-blockers, diuretics, ACE inhibitors) may require insulin dose adjustments; consult your doctor.
• Beta-blockers and some other medicines may mask symptoms of hypoglycemia; patients should be educated to recognize non-adrenergic signs of low blood sugar.
• Alcohol intake can enhance or reduce insulin effect and increase risk of hypoglycemia; limit and discuss with your healthcare provider.
• Pregnancy and breastfeeding: insulin requirements may change during pregnancy and postpartum. Use only under close medical supervision and frequent blood glucose monitoring.
• Use with caution in elderly patients and those at high risk of hypoglycemia; closer monitoring is recommended.
• Not intended for use in diabetic ketoacidosis; in such cases, intravenous rapid-acting insulin and hospital management are required.
• Patients should be trained in proper injection technique, dose adjustment, recognition and management of hypoglycemia and hyperglycemia, and sick-day rules.
• Keep out of reach of children.

Side Effects:

• Very common: Hypoglycemia (low blood sugar), which may present with sweating, tremor, palpitations, hunger, headache, dizziness, confusion, irritability, blurred vision, or, in severe cases, loss of consciousness, seizures, or coma. Severe hypoglycemia is a medical emergency and requires immediate treatment.
• Common: Injection site reactions such as redness, swelling, itching, or pain; these are usually mild and transient.
• Common: Lipodystrophy (lipoatrophy or lipohypertrophy) at injection sites if rotation is not practiced.
• Uncommon: Edema (fluid retention) and transient visual disturbances during initiation or change of insulin therapy.
• Rare: Generalized allergic reactions, including rash, urticaria, or very rarely severe systemic hypersensitivity (anaphylaxis) requiring urgent medical attention.
• Weight gain may occur with improved metabolic control and increased insulin doses.
• Seek immediate medical attention if you experience severe hypoglycemia, difficulty breathing, swelling of face or throat, severe rash, or persistent injection site reactions.

Storage Instructions:

Store unopened vials in a refrigerator at 2–8°c. Do not freeze and do not use if the insulin has been frozen. Keep vials in the outer carton to protect from light. Once in use, follow the manufacturer’s and your pharmacist’s instructions; typically, in-use vials or cartridges can be kept at room temperature below 25–30°c for a limited period (exact in-use shelf life is not provided here and must be checked on the package leaflet). Store in a cool, dry place away from direct sunlight and heat sources. Keep container tightly closed where applicable. Keep out of reach of children.

Specifications:

• Product type: Prescription human insulin medicine for diabetes management.
• Form: Injectable insulin suspension for use in pen devices (Penfill vials/cartridges).
• Strength: 100 iu/ml total human insulin (30% soluble human insulin, 70% isophane protamine human insulin).
• Pack size: 5 vials/cartridges suitable for compatible insulin pens.
• Intended users: Adults and children with type 1 or type 2 diabetes mellitus, as prescribed by a healthcare professional.

Disclaimer:
All pharmacy products are intended for general use only and do not replace professional medical advice, diagnosis, or treatment. Always consult a healthcare provider before use. Results may vary, and no specific outcomes are guaranteed. Products are not intended to diagnose, treat, cure, or prevent any disease unless stated. Follow label instructions carefully, as misuse may cause adverse effects. Compliance with local laws is the customer’s responsibility.